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Can I read Structure-activity relationship homology (SARAH): a conceptual framework for drug discovery in the genomic era on EtoBox?

Structure-activity relationship homology (SARAH): a conceptual framework for drug discovery in the genomic era by Stephen V Frye is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Structure-activity relationship homology (SARAH): a conceptual framework for drug discovery in the genomic era about?

Extension of the traditional pharmacological approach of protein target dassification to whole target systems has the potential to relate elements of protein sequence to the structure-activity relationship (SAR) of small molecules that can modulate protein action. Grouping potential drug discovery targets into families based on the relatedness of their SAR provides a means to translate the information from genome-sequencing efforts into knowledge that will aid in the discovery of drugs.

Who reads Structure-activity relationship homology (SARAH): a conceptual framework for drug discovery in the genomic era?

It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.

Author
Stephen V Frye
Publisher
Elsevier Science; Elsevier ; Cell Press; Elsevier BV (ISSN 1074-5521)
Published
1999
Language
EN
Field
Biochemistry, Genetics and Molecular Biology (Life Sciences)

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