Can I read Novel Therapies for the Prevention of Fibrosis in Glaucoma Filtration Surgery on EtoBox?

Novel Therapies for the Prevention of Fibrosis in Glaucoma Filtration Surgery by Christine G. Shao; Nishant R. Sinha; Rajiv R. Mohan; Aaron D. Webel is a Medicine article available to read on EtoBox.

What is Novel Therapies for the Prevention of Fibrosis in Glaucoma Filtration Surgery about?

Conjunctival fibrosis remains the major impediment to the success of glaucoma filtration surgery. Anti-metabolites remain the gold standard for mitigating post-surgical fibrosis, but they are associated with high complication rates and surgical failure rates. Establishing a more targeted approach to attenuate conjunctival fibrosis may revolutionize the surgical approach to glaucoma. A new strategy is needed to prevent progressive tissue remodeling and formation of a fibrotic scar, subsequently increasing surgical success and reducing the prevalence of glaucoma-related vision loss. Advancements in our understanding of molecular signaling and biomechanical cues in the conjunctival tissue architecture are broadening the horizon for new therapies and biomaterials for the mitigation of fibrosis. This review aims to highlight the strategies and current state of promising future approaches for targeting fibrosis in glaucoma filtration surgery.

Who reads Novel Therapies for the Prevention of Fibrosis in Glaucoma Filtration Surgery?

Author

Christine G. Shao; Nishant R. Sinha; Rajiv R. Mohan; Aaron D. Webel

Publisher

MDPI AG

Published

2023

Language

EN

Field

Medicine (Health Sciences)