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Can I read Release of Sodium Salicylate from Vinyl Alcohol/n‐alkyl Vinyl Carbonate Copolymers on EtoBox?
Release of Sodium Salicylate from Vinyl Alcohol/n‐alkyl Vinyl Carbonate Copolymers by Sánchez-Chaves, Manuel ;Arranz, Félix is a Chemistry article available to read on EtoBox.
What is Release of Sodium Salicylate from Vinyl Alcohol/n‐alkyl Vinyl Carbonate Copolymers about?
This study is concerned with the sodium salicylate release from thin discs of vinyl alcohol/ n-alkyl vinyl carbonate copolymers into an aqueous medium under sink conditions. The drug content of the disc decreases with pseudo-first order rate initially, whereas the drug quantity released is proportional to the square root of time. Data analysis supported the latter treatment, which is in agreement with the diffusional matrix model and invalidates the pseudo-first order assumption. The diffusion coefficient D of vinyl alcohol/ethyl vinyl carbonate copolymers decreases with increasing ethyl vinyl carbonate content whilst D increases as both sodium salicylate concentration and temperature increase. The activation energy of diffusion was found to be 46,03 kJ/mol (1 1 ,00 kcal/mol).
Who reads Release of Sodium Salicylate from Vinyl Alcohol/n‐alkyl Vinyl Carbonate Copolymers?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Sánchez-Chaves, Manuel ;Arranz, Félix
- Publisher
- Wiley (John Wiley & Sons); Wiley (ISSN 0025-116X)
- Published
- 1985
- Language
- EN
- Field
- Chemistry (Physical Sciences)