Can I read Prednisolone: Various toxicities: case report on EtoBox?

Prednisolone: Various toxicities: case report is a Medicine article available to read on EtoBox.

What is Prednisolone: Various toxicities: case report about?

A male child [exact age not stated] developed growth retardation, pubertal delay and rebound effect in the form of flares of idiopathic hypereosinophilic syndrome (IHES) during an off-label treatment with prednisolone for IHES [duration of treatment to reactions onsets not stated; not all outcomes stated]. The boy, who had a history of erythema toxicum neonatorum at birth, asthma, allergic rhinitis and type 1 allergies to birch, cats, peanuts, and dust mites presented with a generalised, itchy, papulonodular skin rash. Based on various findings, he was confirmed to have IHES (FIP1L1-PDGFRA-negative). Therefore, he started receiving an off label treatment with oral prednisolone 25 mg/day (0.9 mg/kg bodyweight) for 10 days and was reduced gradually thereafter. He exhibited a rapid clinical response, almost showing complete remission of the skin rash and decreased blood eosinophilia. However, he developed numerous flares on tapering prednisolone dose, for which he was kept on consistent maintenance prednisolone therapy for many years, associated with growth retardation and pubertal delay. Various attempts were made with various immunosuppressants including hydroxycarbamide [hydroxyure

Who reads Prednisolone: Various toxicities: case report?

Publisher

Adis International Limited (now part of Wolters Kluwer Health); Springer-Verlag; Springer Science and Business Media LLC (ISSN 0114-9954)

Published

2020

Language

EN

Field

Medicine (Health Sciences)