Can I read Ciprofloxacin Derivatives: Synthesis & Activity on EtoBox?

Ciprofloxacin Derivatives: Synthesis & Activity by abelabebaw19 is a document available to read on EtoBox.

What is Ciprofloxacin Derivatives: Synthesis & Activity about?

The document discusses the synthesis and evaluation of novel ciprofloxacin derivatives with enhanced lipophilicity by introducing a substituted benzyl moiety. The synthesized compounds demonstrated significant antimycobacterial and antibacterial activity, particularly compound 4f, which showed improved potency against various Gram-positive bacteria, including MRSA. The study highlights the potential of these derivatives as effective alternatives to combat bacterial resistance to existing fluoroquinolones.

Author

abelabebaw19

Language

EN