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What is Plasmid Replication Mechanisms Explained about?

Linear plasmids have defined ends unlike circular plasmids. Plasmids can replicate via two main mechanisms: theta replication resembling chromosomal replication, and rolling-circle replication using a single-stranded intermediate. Plasmid copy number is regulated tightly by some plasmids and loosely by others to maintain between 1 to 100 copies per cell. Common mechanisms for regulation include antisense RNAs that inhibit replication initiation and plasmid-encoded Rep proteins that control their own transcr

Author

Raquel Vieira

Language

EN