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What is Repeat Dose Toxicities of Edaravone about?

This study investigates the protective effect of edaravone against chronic renal injury induced by cisplatin in male Wistar rats. Results showed that high doses of edaravone significantly ameliorated renal damage, as evidenced by reduced proximal tubule injury and decreased apoptosis-promoting factors. The findings suggest that edaravone may be a potential therapeutic agent for mitigating cisplatin-induced nephrotoxicity in the chronic phase.

Author

regulatory

Language

EN