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Can I read Roles of Splicing Factors in Hormone-Related Cancer Progression on EtoBox?
Roles of Splicing Factors in Hormone-Related Cancer Progression by Toshihiko Takeiwa; Yuichi Mitobe; Kazuhiro Ikeda; Kuniko Horie-Inoue; Satoshi Inoue is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Roles of Splicing Factors in Hormone-Related Cancer Progression about?
Splicing of mRNA precursor (pre-mRNA) is a mechanism to generate multiple mRNA isoforms from a single pre-mRNA, and it plays an essential role in a variety of biological phenomena and diseases such as cancers. Previous studies have demonstrated that cancer-specific splicing events are involved in various aspects of cancers such as proliferation, migration and response to hormones, suggesting that splicing-targeting therapy can be promising as a new strategy for cancer treatment. In this review, we focus on the splicing regulation by RNA-binding proteins including __Drosophila behavior/human splicing__ (DBHS) family proteins, serine/arginine-rich (SR) proteins and heterogeneous nuclear ribonucleoproteins (hnRNPs) in hormone-related cancers, such as breast and prostate cancers.
Who reads Roles of Splicing Factors in Hormone-Related Cancer Progression?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Toshihiko Takeiwa; Yuichi Mitobe; Kazuhiro Ikeda; Kuniko Horie-Inoue; Satoshi Inoue
- Publisher
- Molecular Diversity Preservation International; MDPI AG; Multidisciplinary Digital Publishing Institute (MDPI); Basel: MDPI Center, 2000- (ISSN 1422-0067)
- Published
- 2020
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)