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The document discusses a standardized EuroFlow 8-color antibody panel designed for highly sensitive minimal residual disease (MRD) measurements in B-cell acute lymphoblastic leukemia (BCP-ALL) patients, achieving a sensitivity comparable to PCR-based methods. The study involved multiple phases of design and evaluation, ultimately validating the method on 377 follow-up samples from 178 BCP-ALL patients, demonstrating a high concordance rate with PCR results. The findings indicate that with sufficient cell ac
- Author
- sreeja raju
- Language
- EN