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Characteristics and laboratory findings on admission to the emergency department among 2873 hospitalized patients with COVID-19: the impact of adjusted laboratory tests in multicenter studies. A multicenter study in Spain (BIOCOVID-Spain study) by Luis García de Guadiana-Romualdo; Daniel Morell-García; Cristian Morales-Indiano; Josep Miquel Bauça; María José Alcaide Martín; Clara Esparza del Valle; Jose I. Gutiérrez Revilla; Eloisa Urrechaga; José M. Álamo; Ana M. Hernando Holgado; María-Carmen Lorenzo-Lozano; Silvia Sánchez Fdez-Pacheco; Patricia de la Hera Cagigal; María A. Juncos Tobarra; Juan A. Vílchez; Isabel Vírseda Chamorro; Irene Gutiérrez Garcia; Yolanda Pastor Murcia; Laura Sahuquillo Frías; Laura Altimira Queral; Elisa Nuez-Zaragoza; Juan Adell Ruiz de León; Alicia Ruiz Ripa; Paloma Salas Gómez-Pablos; Iria Cebreiros López; Amaia Fernández Uriarte; Álex Larruzea; María L. López Yepes; Patricia Esteban Torrella; María C. Zamorano Andrés; Jose Pedregosa Díaz; Cristina Acevedo Alcaraz; Alfonso-L. Blazquez-Manzanera; Ana M. L. Padilla Jiménez; María C. Baamonde Calzada; Marina Vera; Matilde Cháfer Rudilla; Magdalena Canalda Campás; Sara García Muñoz; Luis Vicente Gutiérrez; Laura Jiménez Añón; Alfonso Pérez Martínez; Aurelio Pons Castillo; Ruth González Tamayo; Jorge Férriz Vivancos; Olaia Rodríguez-Fraga; Vicente Ferrer Díaz de Brito Fernández; Vicente Aguadero; María G. García Arévalo; María Arnaldos Carrillo; Mercedes González Morales; María Núñez Gárate; Cristina Ruiz Iruela; Natalia Sancho-Rodríguez; Marti Vila Pérez; José M. Egea-Caparrós; Luis Sáenz; Álvaro Blasco Barbero; Amparo Galán Ortega is a scholarly article available to read on EtoBox.

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Identification of predictors for severe disease progression is key for risk stratification in COVID-19 patients. We aimed to describe the main characteristics and identify the early predictors for severe outcomes among hospitalized patients with COVID-19 in Spain. This was an observational, retrospective cohort study (BIOCOVID-Spain study) including COVID-19 patients admitted to 32 Spanish hospitals. Demographics, comorbidities and laboratory tests were collected. Outcome was in-hospital mortality. For analysis, laboratory tests values were previously adjusted to assure the comparability of results among participants. Cox regression was performed to identify predictors. Study population included 2873 hospitalized COVID-19 patients. Nine variables were independent predictors for in-hospital mortality, including creatinine (Hazard ratio [HR]:1.327; 95% Confidence Interval [CI]: 1.040-1.695, = .023), troponin (HR: 2.150; 95% CI: 1.155-4.001; = .016), platelet count (HR: 0.994; 95% CI: 0.989-0.998; = .004) and C-reactive protein (HR: 1.037; 95% CI: 1.006-1.068; = .019). This is the first multicenter study in which an effort was carried out to adjust the results of laboratory tests

Author

Luis García de Guadiana-Romualdo; Daniel Morell-García; Cristian Morales-Indiano; Josep Miquel Bauça; María José Alcaide Martín; Clara Esparza del Valle; Jose I. Gutiérrez Revilla; Eloisa Urrechaga; José M. Álamo; Ana M. Hernando Holgado; María-Carmen Lorenzo-Lozano; Silvia Sánchez Fdez-Pacheco; Patricia de la Hera Cagigal; María A. Juncos Tobarra; Juan A. Vílchez; Isabel Vírseda Chamorro; Irene Gutiérrez Garcia; Yolanda Pastor Murcia; Laura Sahuquillo Frías; Laura Altimira Queral; Elisa Nuez-Zaragoza; Juan Adell Ruiz de León; Alicia Ruiz Ripa; Paloma Salas Gómez-Pablos; Iria Cebreiros López; Amaia Fernández Uriarte; Álex Larruzea; María L. López Yepes; Patricia Esteban Torrella; María C. Zamorano Andrés; Jose Pedregosa Díaz; Cristina Acevedo Alcaraz; Alfonso-L. Blazquez-Manzanera; Ana M. L. Padilla Jiménez; María C. Baamonde Calzada; Marina Vera; Matilde Cháfer Rudilla; Magdalena Canalda Campás; Sara García Muñoz; Luis Vicente Gutiérrez; Laura Jiménez Añón; Alfonso Pérez Martínez; Aurelio Pons Castillo; Ruth González Tamayo; Jorge Férriz Vivancos; Olaia Rodríguez-Fraga; Vicente Ferrer Díaz de Brito Fernández; Vicente Aguadero; María G. García Arévalo; María Arnaldos Carrillo; Mercedes González Morales; María Núñez Gárate; Cristina Ruiz Iruela; Natalia Sancho-Rodríguez; Marti Vila Pérez; José M. Egea-Caparrós; Luis Sáenz; Álvaro Blasco Barbero; Amparo Galán Ortega

Publisher

Informa UK Limited

Published

2021

Language

EN