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Trends in Management of Intracranial Meningiomas: Analysis of 49,921 Cases from Modern Cohort by Vijay Agarwal; Brandon A. McCutcheon; Joshua D. Hughes; Matthew L. Carlson; Amy E. Glasgow; Elizabeth B. Habermann; Quoc-Bao Nguyen; Michael J. Link; Jamie J. Van Gompel is a Medicine article available to read on EtoBox.

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## Objective: We sought to characterize patterns and treatment for intracranial meningiomas in the surveillance, epidemiology, and end results set of cancer registries. ## Methods: Seer data was queried from 2004-2012 for cases of intracranial meningioma using appropriate topography and histology codes. ## Results: A total of 49,921 patients with intracranial meningioma were identified. the vast majority of cases were associated with a benign histology (n = 47,047, 94.2%). there were 21,145 patients (42.4%) who underwent surgical management, 2783 who received radiation alone (5.6%), and 25,993 who underwent surveillance only (52.1%). surgical management decreased in frequency from 48.8% of all cases in 2004 to 38.3% of cases in 2012 (p < 0.001). radiation alone remained stable over time with a range of 4.8%-6.3% of cases. observation increased from 45.0% of cases in 2004 to 56.7% of cases in 2012 (p < 0.001). on unadjusted analysis, surgical management was associated with younger age and larger tumor size. the incidence of tumors <2 cm in size increased significantly over the study period from 29.7% in 2004 to 41.7% in 2012 (p < 0.001). after adjusting for tumor size, multivariable

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Author

Vijay Agarwal; Brandon A. McCutcheon; Joshua D. Hughes; Matthew L. Carlson; Amy E. Glasgow; Elizabeth B. Habermann; Quoc-Bao Nguyen; Michael J. Link; Jamie J. Van Gompel

Publisher

Elsevier BV

Published

2017

Language

EN

Field

Medicine (Health Sciences)