About this Medicine article
Iron, folic acid, and multiple micronutrient supplementation strategies during pregnancy and adverse birth outcomes in Botswana by Caniglia, Ellen C (author);Zash, Rebecca (author);Swanson, Sonja A (author);Smith, Emily (author);Sudfeld, Christopher (author);Finkelstein, Julia L (author);Diseko, Modiegi (author);Mayondi, Gloria (author);Mmalane, Mompati (author);Makhema, Joseph (author);Fawzi, Wafaie (author);Lockman, Shahin (author);Shapiro, Roger L (author) is a Medicine article available to read on EtoBox.
## Summary ## Background Antenatal multiple micronutrient supplementation (MMS) with iron, folic acid, and other micronutrients might improve birth outcomes, but it is not currently universally recommended by WHO. ## Methods In this observational cohort study, we surveyed pregnancies for adverse birth outcomes at eight hospitals from July, 2014, to July, 2018, and 18 hospitals from August, 2018, to December, 2020, in Botswana to assess four routine supplementation strategies in women presenting before 24 weeks’ gestation: folic acid only, iron only, iron and folic acid supplementation (IFAS), and MMS. Women with singleton pregnancies; a known HIV status, age, and delivery site; haemoglobin measured within 7 days of presenting to antenatal care; and weight measured within 31 days of presenting to care were included in our analysis. Data were abstracted from the maternity obstetric record (a record of antenatal care) at the time of birth from all women giving birth at selected hospitals throughout the country. We estimated risk differences overall and in key subgroups, adjusting for demographic and clinical factors. ## Findings Between July 6, 2014, and Dec 8, 2020, 96 341 eligible w
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- Author
- Caniglia, Ellen C (author);Zash, Rebecca (author);Swanson, Sonja A (author);Smith, Emily (author);Sudfeld, Christopher (author);Finkelstein, Julia L (author);Diseko, Modiegi (author);Mayondi, Gloria (author);Mmalane, Mompati (author);Makhema, Joseph (author);Fawzi, Wafaie (author);Lockman, Shahin (author);Shapiro, Roger L (author)
- Publisher
- Elsevier BV
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)