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Can I read Decreased Aortic Early Atherosclerosis and Associated Risk Factors in Hypercholesterolemic Hamsters Fed a High- or Mid-oleic Acid Oil Compared to a High-linoleic Acid Oil on EtoBox?
Decreased Aortic Early Atherosclerosis and Associated Risk Factors in Hypercholesterolemic Hamsters Fed a High- or Mid-oleic Acid Oil Compared to a High-linoleic Acid Oil by Robert J. Nicolosi; Benjamin Woolfrey; Thomas A. Wilson; Patrick Scollin; Garry Handelman; Robert Fisher is a Medicine article available to read on EtoBox.
What is Decreased Aortic Early Atherosclerosis and Associated Risk Factors in Hypercholesterolemic Hamsters Fed a High- or Mid-oleic Acid Oil Compared to a High-linoleic Acid Oil about?
Currently, diets higher in polyunsaturated fat are believed to lower blood cholesterol concentrations, and thus reduce atherosclerosis, greater than diets containing high amounts of saturated or possibly even monounsaturated fat. The present study was designed to investigate the effect of diets containing mid-or high-linoleic oil versus the typical high-linoleic sunflower oil on LDL oxidation and the development of early atherosclerosis in a hypercholesterolemic hamster model. Animals were fed a hypercholesterolemic diet containing 10% mid-oleic sunflower oil, high-oleic olive oil, or high-linoleic sunflower oil (wt/wt) plus 0.4% cholesterol (wt/wt) for 10 weeks. After 10 weeks of dietary treatment, only the animals fed the mid-oleic sunflower oil had significant reductions in plasma LDL-C levels (Ϫ17%) compared to the high-linoleic sunflower oil group. The high-oleic olive oil-fed hamsters had significantly higher plasma triglyceride levels (ϩ41%) compared to the high-linoleic sunflower oil-fed hamsters. The tocopherol levels in plasma LDL were significantly higher in hamsters fed the mid-oleic sunflower oil (ϩ77%) compared to hamsters fed either the high-linoleic sunflower or hig
Who reads Decreased Aortic Early Atherosclerosis and Associated Risk Factors in Hypercholesterolemic Hamsters Fed a High- or Mid-oleic Acid Oil Compared to a High-linoleic Acid Oil?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Robert J. Nicolosi; Benjamin Woolfrey; Thomas A. Wilson; Patrick Scollin; Garry Handelman; Robert Fisher
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0955-2863)
- Published
- 2004
- Language
- EN
- Field
- Medicine (Health Sciences)