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Human papillomavirus infection in lung and esophageal cancers: Analysis of 485 Asian cases by Akiteru Goto; Chih‐Ping Li; Satoshi Ota; Toshiro Niki; Yuji Ohtsuki; Shinichi Kitajima; Suguru Yonezawa; Chihaya Koriyama; Suminori Akiba; Hisataka Uchima; Yueh‐Min Lin; Kun‐Tu Yeh; Jae‐Soo Koh; Chul‐Woo Kim; Kun‐Yong Kwon; Min En Nga; Masashi Fukayama is a Medicine article available to read on EtoBox.
What is Human papillomavirus infection in lung and esophageal cancers: Analysis of 485 Asian cases about?
## Abstract The role of human papillomavirus (HPV) in the development of lung and esophageal cancer remains inconclusive, which is in contrast to the established role HPV plays in the development of uterine cervical cancer. One of the reasons for this is the difference among reported HPV infection rates in these cancers. An analysis of 485 lung and esophageal cancers (176 lung squamous cell carcinoma, 128 lung adenocarcinoma, 181 esophageal carcinoma) in eight institutions in Asia (Tokyo, Kochi, Kagoshima, and Okinawa, Japan; Seoul and Daegu, Korea; Changhua, Republic of China (Taiwan); Singapore, Singapore) was carried out in order to clarify infection rates with HPV. Samples were examined in one laboratory of the Department of Pathology, the University of Tokyo, Japan in order to avoid inter‐laboratory variation using a combination of polymerase chain reaction and in situ hybridization (ISH). HPV was found in 6.3%, 7%, and 9.4% of patients with lung squamous cell carcinoma, lung adenocarcinoma, and esophageal cancer, respectively. Among the geographic areas surveyed, Kagoshima exhibited a significantly higher prevalence of HPV infection in cases of esophageal carcinoma (24.1%). T
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- Author
- Akiteru Goto; Chih‐Ping Li; Satoshi Ota; Toshiro Niki; Yuji Ohtsuki; Shinichi Kitajima; Suguru Yonezawa; Chihaya Koriyama; Suminori Akiba; Hisataka Uchima; Yueh‐Min Lin; Kun‐Tu Yeh; Jae‐Soo Koh; Chul‐Woo Kim; Kun‐Yong Kwon; Min En Nga; Masashi Fukayama
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square (ISSN 0146-6615)
- Published
- 2011
- Language
- EN
- Field
- Medicine (Health Sciences)