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miR-122 by valentina burgos is a document available to read on EtoBox.
1) Researchers inhibited the liver-specific microRNA miR-122 in mice using antisense oligonucleotides to study its role in metabolism. 2) Inhibition of miR-122 resulted in reduced plasma cholesterol, increased fatty acid oxidation in the liver, and decreased fatty acid and cholesterol synthesis. 3) Inhibiting miR-122 in a mouse model of diet-induced obesity also led to reduced liver fat content and plasma cholesterol, along with decreases in genes that promote fat synthesis. This suggests miR-122 regulate
- Author
- valentina burgos
- Language
- EN