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10 Mesenchymal stem cells as a strategy for the treatment of multiple sclerosis and other diseases of the central nervous system by Gross, Gerhard; Häupl, Thomas; Almeida-Porada, Graca; Bühler, Leo; Camara, Niels Olsen Saraiva; Charbord, Pierre; DeClerck, Yves A.; Dennis, James E.; Gonelle-Gispert, Carmen; Kastrup, Jens; Kurtz, Andreas; Pileggi, Antonello; Rojas, Mauricio; Ringdén, Olle; Tyndall, Alan; Uccelli, Antonio; Weiss, Daniel; Wraith, David; Wu, Jian is a scholarly article available to read on EtoBox.

What is 10 Mesenchymal stem cells as a strategy for the treatment of multiple sclerosis and other diseases of the central nervous system about?

<!doctype html public "-//w3c//dtd html 4.0 transitional//en"> <html><head> <meta content="text/html; charset=iso-8859-1" http-equiv=content-type> <meta name=generator content="mshtml 8.00.6001.19412"></head> <body> <P>Multipotent mesenchymal stem cells (MSCs) are a heterogeneous population of cells which reside in a variety of tissues. They differentiate into several mesodermal lineages, secrete a multitude of trophic factors and contribute to tissue homeostasis. MSCs are able to exert immunosuppressive activities by interfering with inflammatory cytokine production and with T- and B-cell proliferation. These immunomodulating properties make MSCs promising candidates for the treatment of chronic inflammatory and autoimmune disorders. There are, however, certain caveats involved including inappropriate migration of cells in the body, immune rejection, tumor formation, or graft versus host disease (GvHD). <BR />This book investigates the current state of the MSC-dependent therapy of chronic inflammatory disorders and autoimmune diseases. Among the covered topics are GvHD, chronic kidney, liver and lung disease, ischemic heart and inflammatory bowel disease, diabetes, osteoarthritis,

Author

Gross, Gerhard; Häupl, Thomas; Almeida-Porada, Graca; Bühler, Leo; Camara, Niels Olsen Saraiva; Charbord, Pierre; DeClerck, Yves A.; Dennis, James E.; Gonelle-Gispert, Carmen; Kastrup, Jens; Kurtz, Andreas; Pileggi, Antonello; Rojas, Mauricio; Ringdén, Olle; Tyndall, Alan; Uccelli, Antonio; Weiss, Daniel; Wraith, David; Wu, Jian

Publisher

Saur, K. G., Verlag. ein Imprint der Walter de Gruyter GmbH

Published

2013

Language

EN

ISBN

9783110298260