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What is The rs10455872-G Allele of The LPA Gene Is Associated With High about?

This study investigates the association between LPA gene polymorphisms and lipoprotein(a) levels as well as aortic valve calcification (AVC) in a Mexican-Mestizo population. The rs10455872-G allele was found to significantly increase the risk of high Lp(a) levels and AVC, with carriers showing a 3.86 and 2.54 times higher risk, respectively. The findings highlight the importance of genetic factors in cardiovascular risk assessment among different ethnic groups.

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estud5366

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EN