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Undiagnosed Asthma-COPD overlap among patients diagnosed as Asthma and COPD in a referral hospital, India by Jefferson Daniel; Richa Gupta; Balamugesh Thangakunam; Devasahayam Jesudas Christopher is a Medicine article available to read on EtoBox.

What is Undiagnosed Asthma-COPD overlap among patients diagnosed as Asthma and COPD in a referral hospital, India about?

Patients who have features of both Asthma & COPD are now known as Asthma COPD overlap (ACO). Prevalence of ACO based on the Global Initiative for Asthma (GINA) and Global initiative for obstructive lung disease (GOLD) Syndromic Approach is scarce. In this cross-sectional observational study, we recruited physician-diagnosed–pAsthma, pCOPD & pACO by simple random sampling. Clinical features, spirometry, 6-min walk test, Serum Immunoglobulin E, % blood eosinophils and chest x-rays were reviewed. Syndromic approach was applied, and the diagnosis was reclassified accordingly. In all, 877 patients were included (Male = 445, Female = 432). Physician diagnosis for these were: pAsthma–713, pCOPD–157 and pACO–7. They were reclassified using the Syndromic approach as: sAsthma, sCOPD and sACO. The 713 pAsthmatics were reclassified as follows: sAsthma–684 (95.94%), sCOPD–12 (1.68%) and sACO–17 (2.38%). Of the 157 pCOPD patients, 91 (57.96%) were reclassified as sCOPD, 23 (14.6%) as sACO, and 17 (927.38%) as sAsthma. Of the 7 previously diagnosed pACO patients, only 1 (14.28%) was reclassified as sACO, 5 (71.42%) as sAsthma and 1 (14.28%) as sCOPD. sCOPD patients had more exacerbations (52.88%

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Author

Jefferson Daniel; Richa Gupta; Balamugesh Thangakunam; Devasahayam Jesudas Christopher

Publisher

Elsevier BV

Published

2023

Language

EN

Field

Medicine (Physical Sciences)