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Omeprazole Metabolites and DDI Risks by Diego Erick Arenas Sanchez is a document available to read on EtoBox.

What is Omeprazole Metabolites and DDI Risks about?

This study investigates the role of omeprazole metabolites in drug-drug interactions (DDIs) by examining their inhibition of CYP2C19 and CYP3A4. The findings indicate that metabolites significantly contribute to DDI risk assessment, with time-dependent inhibition being a crucial factor. The results suggest that including these metabolites in DDI predictions is essential for accurately evaluating in vivo interactions.

Author

Diego Erick Arenas Sanchez

Language

EN