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Initial Screening for Occult Congenital Ectopia Lentis Based on Ocular Biological Parameters in Preschool Children by Jiaona Jing; Qingwei Meng; Wei Gu; Haixia Cheng; Kun Li; Yuming Li; Qinghuai Liu is a Medicine article available to read on EtoBox.

What is Initial Screening for Occult Congenital Ectopia Lentis Based on Ocular Biological Parameters in Preschool Children about?

## Abstract ## Background This study aimed to identify an initial screening tool for congenital ectopia lentis (CEL) by comparing ocular biological parameters in children with myopia. ## Methods A retrospective case-control study was conducted at one tertiary referral centre, from October 2020 to June 2022. Axial length (AL), corneal curvature (CC), refractive astigmatism (RA), corneal astigmatism (CA), internal astigmatism (IA), the difference between the axis of RA and CA [AXIS(RA-CA)], white-to-white corneal diameter (WTW), and axial length-corneal radius ratio (AL/CR) were compared in 28 eyes of CEL patients, and 60 eyes of myopic patients matched for age and refraction. The spherical equivalent of each eye was < -3.00 D. Area under the curve (AUC) of the receiver operating characteristic curves were calculated. ## Results The differences in RA, AL, mean keratometry (Kmed), maximum keratometry (Kmax), minimum keratometry (Kmin), CA, IA, AXIS(RA-CA), WTW, and AL/CR between the CEL and myopic groups were statistically significant (p < 0.05; p < 0.001; p < 0.001; p < 0.001; p < 0.001; p < 0.05; p < 0.001; p < 0.001; p < 0.001; p < 0.001, respectively). In logistic regression analy

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Author

Jiaona Jing; Qingwei Meng; Wei Gu; Haixia Cheng; Kun Li; Yuming Li; Qinghuai Liu

Publisher

Springer Science and Business Media LLC

Published

2023

Field

Medicine (Health Sciences)