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Transcriptional Regulation of the Warburg Effect in Cancer by SIX1 by Li, Ling; Liang, Yingchun; Kang, Lei; Liu, Yang; Gao, Shan; Chen, Siyu; Li, Ying; You, Wenye; Dong, Qian; Hong, Tian; Yan, Zhifeng; Jin, Shuai; Wang, Tao; Zhao, Wei; Mai, Haixing; Huang, Jun; Han, Xiao; Ji, Quanbo; Song, Qi; Yang, Chao; Zhao, Shixin; Xu, Xiaojie; Ye, Qinong is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Transcriptional Regulation of the Warburg Effect in Cancer by SIX1 about?
Cancer Cell, Corrected proof. doi:10.1016/j.ccell.2018.01.010 Warburg effect,aerobic glycolysis,transcription factor,cancer,microRNA,SIX1 CCELL2604_proof.pdf -1 Transcriptional Regulation of the Warburg Effect in Cancer by SIX1 2 Introduction 2 Results 4 Identification of SIX1 as a Key Regulator of Glycolytic Gene Expression 4 SIX1 Binds SIX1-Responsive Elements to Promote Glycolytic Gene Promoter Activity 4 SIX1 Promotes Glycolytic Gene Expression Largely through Interaction with Histone Acetyltransferases HBO1 and AIB1 6 SIX1 Is Inhibited by miR-548a-3p, which Reduces Glycolytic Gene Expression 8 The miR-548a-3p/SIX1 Axis Regulates Aerobic Glycolysis in Cultured Cells 8 The miR-548a-3p/SIX1 Axis Regulates Glycolysis under Hypoxia 8 Aerobic Glycolysis Is Critical for miR-548a-3p/SIX1 Axis Modulation of Proliferation of Cultured Cancer Cells 10 The miR-548a-3p/SIX1 Axis Regulates Glycolysis and Tumor Growth In Vivo 10 Cancer-Related SIX1 Mutation Increases Its Ability to Promote Glycolytic Gene Expression, Aerobic Glycolysis, and Tumor Growth 10 Clinical Relevance of the miR-548a-3p/SIX1 Axis in Breast Cancer 12 Discussion 14 Supplemental Information 16 Acknowledgments 16 Reference
Who reads Transcriptional Regulation of the Warburg Effect in Cancer by SIX1?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Li, Ling; Liang, Yingchun; Kang, Lei; Liu, Yang; Gao, Shan; Chen, Siyu; Li, Ying; You, Wenye; Dong, Qian; Hong, Tian; Yan, Zhifeng; Jin, Shuai; Wang, Tao; Zhao, Wei; Mai, Haixing; Huang, Jun; Han, Xiao; Ji, Quanbo; Song, Qi; Yang, Chao; Zhao, Shixin; Xu, Xiaojie; Ye, Qinong
- Publisher
- Elsevier Science; Elsevier ; Cell Press; Elsevier BV; Publons (ISSN 1535-6108)
- Published
- 2018
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)