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Disorders of Placental Villous Maturation in Fetal Death by Sunil Jaiman; Roberto Romero; Percy Pacora; Eunjung Jung; Gaurav Bhatti; Lami Yeo; Yeon Mee Kim; Bomi Kim; Chong Jai Kim; Jung-Sun Kim; Faisal Qureshi; Suzanne M. Jacques; Offer Erez; Nardhy Gomez-Lopez; Chaur-Dong Hsu is a Medicine article available to read on EtoBox.

What is Disorders of Placental Villous Maturation in Fetal Death about?

## Abstract ## Objective The aims of this study were to ascertain the frequency of disorders of villous maturation in fetal death and to also delineate other placental histopathologic lesions in fetal death. ## Methods This was a retrospective observational cohort study of fetal deaths occurring among women between January 2004 and January 2016 at Hutzel Women’s Hospital, Detroit, MI, USA. Cases comprised fetuses with death beyond 20 weeks’ gestation. Fetal deaths with congenital anomalies and multiple gestations were excluded. Controls included pregnant women without medical/obstetrical complications and delivered singleton, term (37–42 weeks) neonate with 5-min Apgar score ≥7 and birthweight between the 10^th^and 90^th^percentiles. ## Results Ninety-two percent (132/143) of placentas with fetal death showed placental histologic lesions. Fetal deaths were associated with (1) higher frequency of disorders of villous maturation [44.0% (64/143) vs. 1.0% (4/405), P < 0.0001, prevalence ratio, 44.6; delayed villous maturation, 22% (31/143); accelerated villous maturation, 20% (28/143); and maturation arrest, 4% (5/143)]; (2) higher frequency of maternal vascular malperfusion lesions [7

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Author
Sunil Jaiman; Roberto Romero; Percy Pacora; Eunjung Jung; Gaurav Bhatti; Lami Yeo; Yeon Mee Kim; Bomi Kim; Chong Jai Kim; Jung-Sun Kim; Faisal Qureshi; Suzanne M. Jacques; Offer Erez; Nardhy Gomez-Lopez; Chaur-Dong Hsu
Publisher
Walter de Gruyter GmbH
Published
2020
Language
EN
Field
Medicine (Health Sciences)

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