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A convenient synthesis of 2-C-methyl-d-erythritol 4-phosphate and isotopomers of its precursor by Alexandros E. Koumbis; Stefanos S. Kotoulas; John K. Gallos is a Chemistry article available to read on EtoBox.
What is A convenient synthesis of 2-C-methyl-d-erythritol 4-phosphate and isotopomers of its precursor about?
A new synthetic approach toward 2-C-methyl-D-erythritol 4-phosphate (MEP), a key intermediate in the mevalonate-independent biosynthetic pathway for isoprenoids, and deuterated analogues of its precursor, 2-C-methyl-D-erythritol acetonide, is described. This procedure uses 2-C-methyl-D-erythrose acetonide as starting material and delivers, through a mono-protection strategy, the target compounds in a short way and in high yield.
Who reads A convenient synthesis of 2-C-methyl-d-erythritol 4-phosphate and isotopomers of its precursor?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Alexandros E. Koumbis; Stefanos S. Kotoulas; John K. Gallos
- Publisher
- Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0040-4020)
- Published
- 2007
- Language
- EN
- Field
- Chemistry (Physical Sciences)
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