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Anthrax Lethal Toxin Disrupts Intestinal Barrier Function and Causes Systemic Infections With Enteric Bacteria 2012 by fer123wiz is a document available to read on EtoBox.
Anthrax lethal toxin (LT) disrupts intestinal barrier function and causes systemic infections with enteric bacteria. LT-dependent intestinal pathology depends upon its proteolytic activity and is partially attenuated by co-administration of broad spectrum antibiotics. This suggests targeting of MAPK signaling pathways by anthrax LT compromises the structural integrity of the mucosal layer, serving to undermine the effectiveness of the intestinal barrier.
- Author
- fer123wiz
- Language
- EN