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Can I read Critical Appraisal of Oncological Safety of Stent as Bridge to Surgery in Left-sided Obstructing Colon Cancer; a Systematic Review and Meta-analysis on EtoBox?

Critical Appraisal of Oncological Safety of Stent as Bridge to Surgery in Left-sided Obstructing Colon Cancer; a Systematic Review and Meta-analysis by Amelung, Femke J.; Burghgraef, Thijs A.; Tanis, Pieter J.; van Hooft, Jeanin E.; ter Borg, Frank; Siersema, Peter D.; Bemelman, Willem A.; Consten, Esther C.J. is a Medicine article available to read on EtoBox.

What is Critical Appraisal of Oncological Safety of Stent as Bridge to Surgery in Left-sided Obstructing Colon Cancer; a Systematic Review and Meta-analysis about?

This meta-analysis aims to determine the long-term oncological outcomes of SEMS as bridge to surgery (BTS) versus emergency surgery (ES). A systematic search without restrictions was conducted, and all studies comparing SEMS with ES reporting on long-term outcomes were included. Methodological quality was assessed using the appropriate tools. Twenty-one comparative studies were selected, reporting on 1919 patients. Meta-analysis showed no significant difference regarding three- and five-year overall survival (OR = 0·85 (0·68-1·08) and OR = 1·04 (0·68-1·57), respectively), disease-free survival (OR = 0·96 (0·73-1·26) and OR = 0·86 (0·54-1·36), respectively) and local recurrence rate (OR = 1·32 (0·78-2·23)). Permanent stomas were significantly lower in the SEMS group (OR 0·49 (0·32-0·74)). Sensitivity analysis on three-year survival showed opposite outcomes, with a trend towards worse survival in the SEMS group when only RCTs are taken into account. In conclusion, when in experienced hands, SEMS placement as BTS seems oncologically safe.

Who reads Critical Appraisal of Oncological Safety of Stent as Bridge to Surgery in Left-sided Obstructing Colon Cancer; a Systematic Review and Meta-analysis?

It is typically read by researchers, students, and practitioners in Medicine.

Author
Amelung, Femke J.; Burghgraef, Thijs A.; Tanis, Pieter J.; van Hooft, Jeanin E.; ter Borg, Frank; Siersema, Peter D.; Bemelman, Willem A.; Consten, Esther C.J.
Publisher
Elsevier Science; Elsevier ; Elsevier BV (ISSN 1040-8428)
Published
2018
Language
EN
Field
Medicine (Health Sciences)

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