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Effects of System-Level Factors on Race/Ethnic Differences in In-Hospital Mortality after Acute Ischemic Stroke by Philip Sun; Daniela Markovic; Abdullah Ibish; Roland Faigle; Rebecca Gottesman; Amytis Towfighi is a scholarly article available to read on EtoBox.

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## Introduction: Stroke mortality has declined, with differential changes by race; stroke is now the 5th leading cause of death overall, but 2nd leading cause of death in Black individuals. Little is known about recent race/ethnic and sex trends in in-hospital mortality after acute ischemic stroke (AIS) and whether system-level factors contribute to possible differences. ## Methods: Using the National Inpatient Sample, adults (≥18 years) with a primary diagnosis of AIS from 2006 to 2017 (n=643,912) were identified. We assessed in-hospital mortality by race/ethnicity (White, Black, Hispanic, Asian/Pacific Islander [API], other), sex, and age. Hospitals were categorized by proportion of non-White patients served: <25% (“predominantly White patients”), 25–50% (“mixed race/ethnicity profile”), and ≥50% (“predominantly non-White patients”). Using survey adjusted logistic regression, the association between race/ethnicity and odds of mortality was assessed, adjusting for key sociodemographic, clinical, and hospital characteristics (e.g., age, comorbidities, stroke severity, do not resuscitate orders, and palliative care). ## Results: Overall, mortality decreased from 5.0% in 2006 to 2.9%

Author

Philip Sun; Daniela Markovic; Abdullah Ibish; Roland Faigle; Rebecca Gottesman; Amytis Towfighi

Publisher

Cold Spring Harbor Laboratory

Published

2023