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In Vivo proton spectroscopy and spectroscopic imaging of {1‐^13^C}‐g1ucose and its metabolic products by Peter C. M. Van Zijl; A. Scott Chesnick; D. Despres; Chrit T. W. Moonen; J. Rhiz‐Cabello; P. Van Gelderen is a Medicine article available to read on EtoBox.

What is In Vivo proton spectroscopy and spectroscopic imaging of {1‐^13^C}‐g1ucose and its metabolic products about?

## Abstract Metaibolism of {1−^13^C}‐glucose was studied in situ in cat brain usinig gradient‐enhanced proton‐detected heteronuclear spectroscopy. Proton detection of {1−^13^C}‐glucose, {3−^13^C}−lactaite, 4−{^13^C}‐glutamine, 4−{^13^C}‐glutamate and the combined signals 2−{^13^C}‐glutamate/glutamine and 3−(^13^C}‐glutamate/glutamine was achieved, despite the fact that some of the associated proton resonances are close to the water signal. Two‐dimensional {^1^H‐^13^C}‐spectra demonstrate the possibility of __in situ__ spectral assignment with ^1^H sensitivity and ^13^C resolution. Spectroscopic images of glucose and its metabolic products were also acquired, showing the possibility to study spatial dependence of metabolism.

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Author
Peter C. M. Van Zijl; A. Scott Chesnick; D. Despres; Chrit T. W. Moonen; J. Rhiz‐Cabello; P. Van Gelderen
Publisher
John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0740-3194)
Published
1993
Language
EN
Field
Medicine (Health Sciences)

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