Can I read Anticancer Oxadiazol-Pyrazole Derivatives on EtoBox?
Anticancer Oxadiazol-Pyrazole Derivatives by Rômulo Gabriel de Miranda de Paula PInto is a document available to read on EtoBox.
What is Anticancer Oxadiazol-Pyrazole Derivatives about?
This study presents the synthesis of 1,3,4-oxadiazol-2-yl-pyrazole derivatives with potential anticancer properties, particularly against the MCF-7 breast cancer cell line. Compound 7c demonstrated superior cytotoxicity compared to Tamoxifen, while other compounds showed varying degrees of activity. The research highlights the importance of these derivatives as antiangiogenic agents by inhibiting the VEGF-VEGFR2 complex, which is crucial for cancer progression.
- Author
- Rômulo Gabriel de Miranda de Paula PInto
- Language
- EN