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Assessment and correlation of the influence of non‐surgical periodontal therapy on serum lipid profile and cytokines in patients with stage III periodontitis by Abhay Pandurang Kolte; Rajashri Abhay Kolte; Pranjali Vijaykumar Bawankar; Vinisha Ashok Bajaj is a Dentistry article available to read on EtoBox.
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## Abstract ## Background Interleukins are the markers of inflammation and the lipid profile reveals the likelihood of arising cardiovascular disease (CVD). The present study aimed to assess and correlate the influence of non‐surgical periodontal therapy (NSPT) on serum lipid profile and Interleukin‐6 (IL‐6) and Interleukin‐8 (IL‐8) in patients with Stage III periodontitis. ## Methods Sixty patients with the age range of 35–60 years with Stage III periodontitis were included by evaluating for periodontal parameters such as Probing pocket depth (PPD) and clinical attachment levels (CAL). NSPT was performed at baseline, 3 and 6 months. Biochemical parameters like serum lipid parameters of total cholesterol (TC), triglycerides (TG), low‐density lipopolysaccharide (LDL), high‐density lipopolysaccharide (HDL), and IL‐6 and IL‐8 serum levels were assessed at baseline and 6 months' post‐NSPT. ## Results The results indicated a significant reduction (p < 0.0001) in the PPD (2.75 ± 0.41), CAL (3.23 ± 0.56), lipid profile, and serum cytokine levels 6 months' post‐NSPT as compared to baseline. A highly significant (p < 0.0001) percentage reduction was observed in the IL‐6 (35.3%), IL‐8 (41.6%
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- Author
- Abhay Pandurang Kolte; Rajashri Abhay Kolte; Pranjali Vijaykumar Bawankar; Vinisha Ashok Bajaj
- Publisher
- Wiley
- Published
- 2022
- Language
- EN
- Field
- Dentistry (Health Sciences)