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The Portfolio Diet and Incident Type 2 Diabetes: Findings From the Women’s Health Initiative Prospective Cohort Study by Andrea J. Glenn; Jie Li; Kenneth Lo; David J.A. Jenkins; Beatrice A. Boucher; Anthony J. Hanley; Cyril W.C. Kendall; Aladdin H. Shadyab; Lesley F. Tinker; Steven D. Chessler; Barbara V. Howard; Simin Liu; John L. Sievenpiper is a Medicine article available to read on EtoBox.
What is The Portfolio Diet and Incident Type 2 Diabetes: Findings From the Women’s Health Initiative Prospective Cohort Study about?
## OBJECTIVE A plant-based dietary pattern, the Portfolio Diet, has been shown to lower LDL cholesterol and other cardiovascular disease risk factors. However, no study has evaluated the association of this diet with incident type 2 diabetes. ## RESEARCH DESIGN AND METHODS This analysis included 145,299 postmenopausal women free of diabetes at baseline in the Women’s Health Initiative (WHI) Clinical Trials and Observational Study from 1993 to 2021. Adherence to the diet was assessed with a score based on six components (high in plant protein [soy and pulses], nuts, viscous fiber, plant sterols, and monounsaturated fat and low in saturated fat and cholesterol) determined from a validated food-frequency questionnaire. We used Cox proportional hazards models to estimate hazard ratios (HRs) and 95% CIs of the association of the Portfolio Diet, alongside the Dietary Approaches to Stop Hypertension (DASH) and Mediterranean diets, with incident type 2 diabetes, with adjustment for potential confounders. ## RESULTS Over a mean follow-up of 16.0 years, 13,943 cases of incident type 2 diabetes were identified. In comparisons of the highest with the lowest quintiles of adherence, the HRs for
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- Author
- Andrea J. Glenn; Jie Li; Kenneth Lo; David J.A. Jenkins; Beatrice A. Boucher; Anthony J. Hanley; Cyril W.C. Kendall; Aladdin H. Shadyab; Lesley F. Tinker; Steven D. Chessler; Barbara V. Howard; Simin Liu; John L. Sievenpiper
- Publisher
- American Diabetes Association
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)