Can I read An Improved Animal Model for Studying Desferrioxamine on EtoBox?
An Improved Animal Model for Studying Desferrioxamine by A. Steward; I. Williamson; T. Madigan; A. BRETNALL; F. Hassan is a Medicine article available to read on EtoBox.
What is An Improved Animal Model for Studying Desferrioxamine about?
A hamster model has been developed for studying desferrioxamine. The hamster shows many similarities to man in terms of plasma stability and metabolites formed from desferrioxamine. The [^59^Fe]ferritin derived from rats has been shown to be sequestered into liver parenchymal cells when injected intravenously into hamsters. The technique has proved sufficiently sensitive to enable detection of differences of intravenous (6.25%) > oral (3.66%) > control (2.19%). A dose–response relationship was demonstrated using the intravenous dose route. The model offers a simple method for comparing the efficacy of administration routes for determining the optimal use of desferrioxamine.
Who reads An Improved Animal Model for Studying Desferrioxamine?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- A. Steward; I. Williamson; T. Madigan; A. BRETNALL; F. Hassan
- Publisher
- John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0007-1048)
- Published
- 1996
- Language
- EN
- Field
- Medicine (Health Sciences)