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Glucose transporter recycling in rat adipose cells. Effects of potassium depletion. by H Nishimura; M.J. Zarnowski; I.A. Simpson is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Glucose transporter recycling in rat adipose cells. Effects of potassium depletion. about?
Depletion of intracellular potassium (K+) induced a 4-fold increase in basal and 1 w phorbol-12-myristate-13-acetate (PMA)-stimulated 3-O-methylglucose transport in rat adipose cells. K+ depletion had no effect on the maximum insulin (0.7 V)-stimulated transport rate but enhanced the sensitivity to insulin 3-fold (EC50= 0.06 uersus 0.16 nm) by a mechanism that did not result from changes in the insulin receptor binding, autophosphorylation, or tyrosine kinase activity. Western blotting analysis revealed that K+ depletion induced a 2.2-fold increase in GLUT4 in plasma membranes from basal cells, enhanced the PMA-stimulated GLUT4 transloca-
Who reads Glucose transporter recycling in rat adipose cells. Effects of potassium depletion.?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- H Nishimura; M.J. Zarnowski; I.A. Simpson
- Publisher
- Elsevier BV
- Published
- 1993
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)
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