Can I read Molecular mechanisms of sweet taste 8: saccharin, acesulfame-K, cyclamate and their derivatives on EtoBox?

Molecular mechanisms of sweet taste 8: saccharin, acesulfame-K, cyclamate and their derivatives by Tetsuo Suami; Leslie Hough; Tomoya Machinami; Takayuki Saito; Katsumi Nakamura is a Agricultural and Biological Sciences article available to read on EtoBox.

What is Molecular mechanisms of sweet taste 8: saccharin, acesulfame-K, cyclamate and their derivatives about?

The sweetness values of saccharin, acesulfame-K and cyclatmate have been rationalised on the basis of molecular models of their multiple interactions with our a-helical protein receptor, in which the hydrophobic attractions within a crevice of the helix are critical for both sweetness and intensity. The study was carried out by modelling of the host-guest molecules, joined by hydrogen bonds and assessment of their non-bonded hydrophobic interactions, as determined by three-dimensional computer graphics. Both enhancement and loss of sweetness in these disulphoxide derivatives were then interpreted on this basic premise.

Who reads Molecular mechanisms of sweet taste 8: saccharin, acesulfame-K, cyclamate and their derivatives?

Author

Tetsuo Suami; Leslie Hough; Tomoya Machinami; Takayuki Saito; Katsumi Nakamura

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0308-8146)

Published

1998

Language

EN

Field

Agricultural and Biological Sciences (Life Sciences)