Opening book details…
Can I read Influence of vitamin C on cadmium absorption and distribution in rats on EtoBox?
Influence of vitamin C on cadmium absorption and distribution in rats by Andrzej Grosicki is a Environmental Science article available to read on EtoBox.
What is Influence of vitamin C on cadmium absorption and distribution in rats about?
The purpose of the present study was to evaluate the effect of a dietary vitamin C supplement on cadmium absorption and distribution in an animal model. An aqueous solution of cadmium chloride (labelled with cadmium-109) was given by gavage to male Wistar rats for 28 days at a daily dose corresponding to 10 mg Cd/kg diet (1.0-1.2 mg Cd/kg b.w.). The animals assigned to groups 1 and 2 (45 animals per group) received a standard laboratory diet LSM, and tap water or tap water supplemented with ascorbic acid (1.5 mg/l), respectively. The radioactivity of the samples was measured using a liquid scintillation counter (tissue samples) and a gas-flow automatic counter (ashed carcasses). The fractional uptake of cadmium-109 in the carcass and organs was evaluated within 32 days after treatment by dividing the cadmium-109 activity in the whole sample by the total activity of cadmium-109 administered for 28 days. Results were compared using AUC (areas under the concentration-time curve) values. The vitamin C supplement decreased the carcass cadmium burden and the cadmium content in the liver, kidneys, testicles and muscles; the highest decreases were found in the testicles, the lowest ones in
Who reads Influence of vitamin C on cadmium absorption and distribution in rats?
It is typically read by researchers, students, and practitioners in Environmental Science.
- Author
- Andrzej Grosicki
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0946-672X)
- Published
- 2004
- Language
- EN
- Field
- Environmental Science (Physical Sciences)