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Association Between Prostate Cancer and Serum Testosterone Levels by Ping L. Zhang; Seymour Rosen; Ravindra Veeramachaneni; Jerry Kao; William C. DeWolf; Glenn Bubley is a Medicine article available to read on EtoBox.

What is Association Between Prostate Cancer and Serum Testosterone Levels about?

## Abstract ## BACKGROUND The purpose of the current study was to determine whether the presence of prostate cancer altered serum testosterone levels. ## METHODS Initially, we evaluated both serum total and free testosterone levels in patients with either high‐grade (n = 18) or moderate‐grade (n = 146) prostate cancer, detected by prostate needle biopsies. Then both serum total and free testosterone levels, before and after prostatectomy, were compared in 79 of the 164 men with prostate cancer. ## RESULTS In the first setting, serum total and free testosterone levels (307 ± 24 ng/dl and 1.14 ± 0.09 ng/dl) in patients with high‐grade prostate cancer were significantly lower than those in patients with moderate‐grade prostate cancer (452 ± 12 ng/dl and 1.51 ± 0.04 ng/dl) and those without prostate cancer (451 ± 17 ng/dl and 1.55 ± 0.06 ng/dl). After prostatectomy in 79 patients with prostate cancer, serum levels of both total and free testosterone (511 ± 15 ng/dl and 1.78 ± 0.05 ng/dl) were found significantly elevated when compared with their respective presurgical total and free testosterone levels (450 ± 17 ng/dl and 1.60 ± 0.06 ng/dl). ## CONCLUSION Our findings show that serum t

Who reads Association Between Prostate Cancer and Serum Testosterone Levels?

Author

Ping L. Zhang; Seymour Rosen; Ravindra Veeramachaneni; Jerry Kao; William C. DeWolf; Glenn Bubley

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0270-4137)

Published

2002

Language

EN

Field

Medicine (Health Sciences)