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An Ultrastuctural Study of Hair Fiber Damage and Restoration Following Treatment with Permanent Hair Dye by Hyung Jin Ahn; Won-Soo Lee is a Medicine article available to read on EtoBox.

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## Abstract **Introduction** Hair fibers are comprised of non‐nucleated keratinocytes and are biologically dead. Clinical damage to the hair shaft occurs with the application of hair dye. Whether this damage can be repaired and the time frame involved is of interest and may help to determine the optimal interval between repeat applications. **Aims and methods** Ultrastructural changes of hair shafts after application of permanent hair dye were observed sequentially in a 26‐year‐old woman. The dye contained __p__‐phenylenediamine, m‐aminophenol, resorcin and hydrogen peroxide as an oxidizer. Scanning and transmission electron microscopy was performed immediately before application of the hair dye and again at 30 min, 1 h, 3 h, 6 h, 1 day, 3 days, 1 week, 2 weeks, 4 weeks, 6 weeks and 8 weeks. **Results** The hair showed cuticular swelling with focal degeneration. In some places there was exposure of the hair cortex due to extensive cuticular detachment. There were many holes of various size in the endocuticle, small focal lacunae along the intercellular space and an ill‐defined A‐layer especially beneath the area of cuticular detachment. The exocuticle appeared normal. The findings

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Author

Hyung Jin Ahn; Won-Soo Lee

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0011-9059)

Published

2002

Language

EN

Field

Medicine (Health Sciences)