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This systematic review and meta-analysis evaluated the effects of higher versus lower oxygen targets in mechanically ventilated adult patients in the ICU. The analysis of eight trials involving 4,415 participants found no significant difference in mortality between the two oxygen targeting strategies, but suggested that targeting normoxemia may reduce mortality compared to hyperoxemia, albeit with low certainty. The findings highlight the need for further research to clarify optimal oxygen therapy targets d

Author

Jose Manuel C T

Language

EN