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Efficient Atorvastatin Synthesis via MCR by Bhausaheb Narsale is a document available to read on EtoBox.
This article presents a novel and efficient synthesis of atorvastatin, a leading cardiovascular drug, utilizing a multicomponent reaction (MCR) approach based on the Ugi reaction. The proposed method significantly reduces the number of synthetic steps to four, compared to the seven steps in traditional methods, enhancing the accessibility of atorvastatin and its derivatives. The authors highlight the advantages of MCR chemistry in drug synthesis, showcasing its potential for generating chemical diversity in
- Author
- Bhausaheb Narsale
- Language
- EN