Opening book details…
Can I read E3 ligase Hei10: a multifaceted structure-based signaling molecule with roles within and beyond meiosis on EtoBox?
E3 ligase Hei10: a multifaceted structure-based signaling molecule with roles within and beyond meiosis by Arnaud De Muyt; Liangran Zhang; Tristan Piolot; Nancy Kleckner; Eric Espagne; Denise Zickler is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is E3 ligase Hei10: a multifaceted structure-based signaling molecule with roles within and beyond meiosis about?
Human enhancer of invasion-10 (Hei10) mediates meiotic recombination and plays important roles in cell proliferation. Here, De Muyt et al. analyzed the function of Hei10 during meiosis and throughout the sexual cycle of the fungus __Sordaria__. The data suggest that Hei10 integrates signals from the synaptonemal complex, recombination complexes, and the cell cycle to mediate the programmed assembly and disassembly of recombination complexes via SUMOylation/ubiquitination. This study delineates the role of Hei10 in regulating meiotic recombination and provides new perspectives on its role outside meiosis.
Who reads E3 ligase Hei10: a multifaceted structure-based signaling molecule with roles within and beyond meiosis?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Arnaud De Muyt; Liangran Zhang; Tristan Piolot; Nancy Kleckner; Eric Espagne; Denise Zickler
- Publisher
- Cold Spring Harbor Laboratory Press; Cold Spring Harbor Laboratory (ISSN 0890-9369)
- Published
- 2014
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)