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Can I read Take a Breath: Oxygen Sensing of Epidermal Differentiation on EtoBox?
Take a Breath: Oxygen Sensing of Epidermal Differentiation by Artem Smirnov; Eleonora Candi is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Take a Breath: Oxygen Sensing of Epidermal Differentiation about?
Skin serves as a barrier to protect our body from injury, pathogens and trans-epidermal water loss. It is the only tissue directly exposed to oxygen besides lungs. Air exposure is an essential step of in vitro generation skin graft. However, the role of oxygen in this process remains hitherto unclear. Teshima et al. unveiled the impact of the hypoxia-inducible factor (HIF) pathway on epidermal differentiation in three-dimensional skin models. The authors of this work describe how air-lifting of organotypic epidermal cultures impairs HIFs activity, leading to a proper terminal differentiation of keratinocytes and stratification.
Who reads Take a Breath: Oxygen Sensing of Epidermal Differentiation?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Artem Smirnov; Eleonora Candi
- Publisher
- Wiley
- Published
- 2023
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)