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An Analysis of Testosterone Implants for Androgen Replacement Therapy by David J. Handelsman; Mary-Anne Mackey; Chris Howe; Leo Turner; Ann J. Conway is a Medicine article available to read on EtoBox.

What is An Analysis of Testosterone Implants for Androgen Replacement Therapy about?

## OBJECTIVE To review 13 years of experience using fused crystalline testosterone implants for androgen replacement therapy in order to identify pattern of usage (including continuation rates) and adverse events emerging during therapy and factors associated with adverse events including implant extrusions. ## DESIGN Retrospective review of prospectively collected data on characteristics of patients and implant procedures performed as well as adverse events reported during routine follow‐up. ## PATIENTS Over 13 years 973 implant procedures using fused crystalline testosterone implants were performed in 221 men. ## MEASUREMENTS Continuation rates and adverse events such as extrusions, bleeding, infection or others were recorded and analysed in relationship to characteristics of the patient and the implant procedure performed. ## RESULTS Overall rate of adverse events (108/973, 11.1%) was significantly related to increased numbers of implants (4.2 ± 0.1 __vs__ 4.0 ± 0.03, __P__ = 0.031) and higher levels of physical activity at work (__P__ = 0.030). The most common adverse effect was extrusion (83/973, 8.5%) which was related to occupational classification (__P__ = 0.033) and increa

Who reads An Analysis of Testosterone Implants for Androgen Replacement Therapy?

Author

David J. Handelsman; Mary-Anne Mackey; Chris Howe; Leo Turner; Ann J. Conway

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley; Research Square (ISSN 0300-0664)

Published

1997

Language

EN

Field

Medicine (Health Sciences)