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Effects of Growth Years on Ginsenoside Biosynthesis of Wild Ginseng and Cultivated Ginseng by Xiaoxue Fang; Manqi Wang; Xinteng Zhou; Huan Wang; Huaying Wang; Hongxing Xiao is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

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## Background Ginsenoside, as the main active substance in ginseng, has the function of treating various diseases. However, the ginsenosides content of cultivated ginseng is obviously affected by the growth years, but the molecular mechanism is not clear. In addition, there are significant differences in morphology and physiology between wild ginseng and cultivated ginseng, and the effect of growth years on ginsenoside synthesis not yet understood in wild ginseng. ## Results Transcriptome sequencing on the roots, stems and leaves of cultivated ginseng and wild ginseng with different growth years was performed in this study, exploring the effect of growth years on gene expression in ginseng. The number of differentially expressed genes (DEGs) from comparison groups in cultivated ginseng was higher than that in wild ginseng. The result of weighted gene co-expression network analysis (WGCNA) showed that growth years significantly affected the gene expression of Mitogen-activated protein kinases (MAPK) signaling pathway and terpenoid backbone biosynthesis pathway in cultivated ginseng, but had no effects in wild ginseng. Furthermore, the growth years had significant effects on the gene

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Author

Xiaoxue Fang; Manqi Wang; Xinteng Zhou; Huan Wang; Huaying Wang; Hongxing Xiao

Publisher

Springer Science and Business Media LLC

Published

2022

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)