About this document
Similarity and Difference Factors in Dissolution by madosb5133 is a document available to read on EtoBox.
The document provides instructions for calculating similarity and difference factors to compare dissolution profiles of two drug products. It defines the number of time points, n, and lists the cumulative percentage dissolved over time for a reference (Rt) and test (Tt) product. To calculate the factors, the differences and sums of the differences between the dissolved percentages over time are used, with the goal of the products being at least 85% similar based on the number of matching time points.
- Author
- madosb5133
- Language
- EN