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Central venous-to-arterial CO2 difference is a poor tool to predict adverse outcomes after cardiac surgery: a retrospective study by Pierre Huette; Christophe Beyls; Jihad Mallat; Lucie Martineau; Patricia Besserve; Guillaume Haye; Mathieu Guilbart; Hervé Dupont; Pierre-Grégoire Guinot; Momar Diouf; Yazine Mahjoub; Osama Abou-Arab is a Medicine article available to read on EtoBox.
What is Central venous-to-arterial CO2 difference is a poor tool to predict adverse outcomes after cardiac surgery: a retrospective study about?
Purpose The venous-to-arterial carbon dioxide partial pressure difference (CO 2 gap) has been reported to be a sensitive indicator of cardiac output adequacy. We aimed to assess whether the CO 2 gap can predict postoperative adverse outcomes after cardiac surgery. Methods A retrospective study was conducted of 5,151 patients from our departmental database who underwent cardiac surgery from 1 January 2008 to 31 December 2018. Lactate level (mmolÁL -1 ), central venous oxygen saturation (ScVO 2 ) (%), and the venous-to-arterial carbon dioxide difference (CO 2 gap) were measured at intensive care unit (ICU) admission and on days 1 and 2 after cardiac surgery. The following postoperative adverse outcomes were collected: ICU mortality, hemopericardium or tamponade, resuscitated cardiac arrest, acute kidney injury, major bleeding, acute hepatic failure, mesenteric ischemia, and pneumonia. The primary outcome was the presence of at least one postoperative adverse outcome. Logistic regression was used to assess the association between ScVO 2 , lactate, and the CO 2 gap with adverse outcomes. Their diagnostic performance was compared using a receiver operating characteristic (ROC) curve. Re
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- Author
- Pierre Huette; Christophe Beyls; Jihad Mallat; Lucie Martineau; Patricia Besserve; Guillaume Haye; Mathieu Guilbart; Hervé Dupont; Pierre-Grégoire Guinot; Momar Diouf; Yazine Mahjoub; Osama Abou-Arab
- Publisher
- Springer Science and Business Media LLC
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)