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What is Glycopeptide Fragmentation in MS/MS Analysis about?

This study investigates the fragmentation characteristics of high mannose N-glycopeptides in tandem mass spectrometry using different charge carriers: doubly protonated, doubly sodiated, and hybrid protonated sodium adduct ions. The results reveal that protonated glycopeptides exhibit a wider range of fragmentation energies and provide both glycan and peptide fragmentation, while sodiated glycopeptides dissociate over a narrower range, yielding only glycan cleavages. The findings highlight the significant i

Author

javiersastretorano

Language

EN