Can I read Neuromyelitis Optica Spectrum Disorders on EtoBox?

Neuromyelitis Optica Spectrum Disorders by Dean M. Wingerchuk is a nonfiction available to read on EtoBox.

What is Neuromyelitis Optica Spectrum Disorders about?

Neuromyelitis optica (NMO) is an inflammatory demyelinating central nervous system disease. It has been classically defined as a monophasic, isolated co-occurrence of optic neuritis and transverse myelitis with uncertain relationship to multiple sclerosis. In the past decade, however, NMO has emerged as a distinct disorder associated with serum antibodies that target the astrocyte water channel aquaporin-4, distinguishing it from multiple sclerosis. The specificity of aquaporin-4 antibodies has led to appreciation of a wider spectrum of clinical and neuroimaging features, termed NMO spectrum disorders (NMOSD), than was encompassed by the classic NMO definition. Moreover, immunopathological studies have demonstrated that aquaporin-4 antibodies have pathogenic potential and that the disorder is a primary astrocytopathy with secondary demyelination. This chapter discusses the clinical definition and diagnosis of NMOSD and approaches to management, many informed by rapid advances in the understanding of NMO pathobiology.

Who reads Neuromyelitis Optica Spectrum Disorders?

Author

Dean M. Wingerchuk

Publisher

Oxford University Press

Published

2016

Language

EN

Category

nonfiction