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What is Fibroblast Origins in Systemic Sclerosis about?

The document discusses the cellular origins of fibroblasts and myofibroblasts, particularly in the context of systemic sclerosis (scleroderma) and related diseases. It highlights the role of epithelial-mesenchymal transition (EMT) and various progenitor cells, including circulating fibrocytes and monocyte-derived mesenchymal progenitors, in the development of these cells. The findings suggest that fibroblasts may arise from multiple sources beyond resident fibroblasts, which could have implications for unde

Author

1756010034

Language

EN