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What is Hyperhomocysteinemia and Cardiovascular Risk about?

Hyperhomocysteinemia is identified as a significant risk factor for cardiovascular disease, primarily due to its role in causing endothelial dysfunction through impaired nitric oxide (NO) availability. The study highlights the potential involvement of asymmetric dimethylarginine (ADMA) as a key mediator in this process, as it inhibits NO synthase and is influenced by homocysteine metabolism. Animal and clinical studies suggest that elevated ADMA levels may unify the mechanisms leading to endothelial dysfunc

Author

naftton14

Language

EN