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Can I read Cutaneous manifestations of chimeric antigen receptor T-cell therapy: An introduction for dermatologists on EtoBox?
Cutaneous manifestations of chimeric antigen receptor T-cell therapy: An introduction for dermatologists by Kelsey B. Nusbaum; Brittany Dulmage; Jennifer N. Choi; Samantha M. Jaglowski; Abraham M. Korman is a Medicine article available to read on EtoBox.
What is Cutaneous manifestations of chimeric antigen receptor T-cell therapy: An introduction for dermatologists about?
Chimeric antigen receptor T-cell therapy is an emerging immunotherapy with promising efficacy for the treatment of previously refractory or relapsed malignancies. As a personalized medicine approach, T cells are genetically engineered to express a receptor designed to bind a specific tumor antigen, leading to selective immune-mediated destruction of tumor cells. Due to the novelty of chimeric antigen receptor T-cell therapy, the safety profile continues to evolve with limited information currently available on cutaneous adverse events. Improved understanding of the spectrum of cutaneous adverse events may facilitate earlier recognition and appropriate management of these toxicities. To explore this knowledge gap, we discuss the available case reports and clinical trial results of cutaneous reactions associated with chimeric antigen receptor T-cell therapy.
Who reads Cutaneous manifestations of chimeric antigen receptor T-cell therapy: An introduction for dermatologists?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Kelsey B. Nusbaum; Brittany Dulmage; Jennifer N. Choi; Samantha M. Jaglowski; Abraham M. Korman
- Publisher
- Elsevier BV
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)