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Efficacy of a New-generation Platelet-rich Fibrin in the Treatment of Periodontal Intrabony Defects: a Randomized Clinical Trial by Boróka Klára Csifó-Nagy; Eleonóra Sólyom; Vera Lili Bognár; Annamária Nevelits; Ferenc Dőri is a Dentistry article available to read on EtoBox.

What is Efficacy of a New-generation Platelet-rich Fibrin in the Treatment of Periodontal Intrabony Defects: a Randomized Clinical Trial about?

## Abstract ## Background The aim of the study was to clinically evaluate the healing of intrabony defects after treatment with a new generation of platelet-rich fibrin (A-PRF+) respect to enamel matrix derivative (EMD). ## Methods Thirty (30) intrabony defects of 18 patients (9 males, 9 females) were randomly treated with A-PRF+ (test, n = 15) or EMD (control, n = 15). The following clinical parameters were recorded at baseline and 6 months after surgery: pocket depth (PD), gingival recession (GR) and clinical attachment level (CAL). After debridement the intrabony defects were filled with A-PRF+ in the test group, respectively with EMD in the control group, and fixed with sutures to ensure wound closure and stability. ## Results Both treatment methods resulted in statistically significant PD reductions, respectively CAL gains six months post-operatively. No statistically significant differences were found between the two groups as the mean CAL gain was 2.33 ± 1.58 mm in the A-PRF+ group, respectively 2.60 ± 1.18 mm in the EMD group (p < 0.001). ## Conclusion Within the limits of this study the new-generation platelet-rich fibrin seems to be as clinically effective as EMD during s

Who reads Efficacy of a New-generation Platelet-rich Fibrin in the Treatment of Periodontal Intrabony Defects: a Randomized Clinical Trial?

Author

Boróka Klára Csifó-Nagy; Eleonóra Sólyom; Vera Lili Bognár; Annamária Nevelits; Ferenc Dőri

Publisher

Springer Science and Business Media LLC

Published

2021

Language

EN

Field

Dentistry (Health Sciences)